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KMID : 1137820210420030116
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의공학회지
2021 Volume.42 No. 3 p.116 ~ p.124
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Development of a Real-time Medical Imaging System Combined with Laser Speckle Contrast Imaging and Fluorescence Imaging
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Shim Min-Jae
Kim Yi-Keun
Ko Taek-Yong
Choi Jin-Hyuk
Ahn Yeh-Chan
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Abstract
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It is important to differentiate between the target tissue (or organ) and the rest of the tissue before incision during surgery. And when it is necessary to preserve the differentiated tissues, the blood vessels connected to the tissue must be preserved together. Various non-invasive medical imaging methods have been developed for this pur?pose. We aimed to develop a medical imaging system that can simultaneously apply fluorescence imaging using indo?cyanine green (ICG) and laser speckle contrast imaging (LSCI) using laser speckle patterns. We designed to collect images directed to the two cameras on a co-axial optical path and to compensate equal optical path length for two optical designs. The light source used for fluorescence and LSCI the same 785 nm wavelength. This system outputs real-time images and is designed to intuitively distinguish target tissues or blood vessels. This system outputs LSCI images up to 37 fps through parallel processing. Fluorescence for ICG and blood flow in animal models were observed throughout the experiment.
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KEYWORD
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Laser speckle image, Fluorescence, Real-time, Parallel computing, Indocyanine green
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